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2 OMIM references -
1 associated gene
10 signs/symptoms
PROTEIN INTERACTIONS: 2
3 OMIM references -
3 associated genes
No signs/symptoms info
Fibronectin glomerulopathy
Frontotemporal dementia with motor neuron disease

FN1 C9ORF72
FUS
TARDBP


INTERACTOME
ASSOCIATIONS

(click on a score value to see the evidence)
FN1
FN1
(0.72)
(0.63)
FUS
TARDBP



Citations in the biomedical literature:


Fibronectin glomerulopathy
FN1
Frontotemporal dementia with motor neuron disease
C9ORF72 FUS TARDBP



Fibronectin glomerulopathy
Frontotemporal dementia with motor neuron disease

Synonym(s):
- GFND
- Glomerulopathy with fibronectin deposits

Synonym(s):
- FTD-ALS
- FTD-MND
- Frontotemporal dementia with amyotrophic lateral sclerosis

Classification (Orphanet):
- Rare genetic disease
- Rare renal disease
Classification (Orphanet):
- Rare genetic disease
- Rare neurologic disease

Classification (ICD10):
- Diseases of the genitourinary system -
Classification (ICD10):
(no data available)

Epidemiological data:
Class of prevalence: <1 / 1 000 000
Average age onset: variable
Average age of death: -
Type of inheritance: autosomal dominant
Epidemiological data:
Class of prevalence: unknown
Average age onset: adulthood
Average age of death: adult
Type of inheritance: autosomal dominant

External references:
2 OMIM references -
No MeSH references
External references:
3 OMIM references -
No MeSH references

Fibronectin glomerulopathy

Very frequent
- Autosomal dominant inheritance
- Chronic arterial hypertension
- Edema of the legs / lower limbs
- Functional anomalies of the kidney and the urinary tract
- Hematuria / microhematuria
- Nephrotic syndrome
- Proteinuria
- Renal failure
- Renal glomerular defect / glomerulopathy

Occasional
- Intracranial / cerebral / meningeal hemorrhage


Frontotemporal dementia with motor neuron disease

(no data available)